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10.1097/MD.0000000000015850 Summary Keywords interleukin-6, C-reactive protein, antioxidant, biomarkers, coenzyme Q10, umbrella meta-analysis Citation Dabbaghi Varnousfaderani S, Musazadeh V, Ghalichi F, Kavyani Z, Razmjouei S, Faghfouri AH, Ahrabi SS, Seyyed Shoura SM and Dehghan P (2023) Alleviating effects of coenzyme Q10 supplements on biomarkers of inflammation and oxidative stress: results from an umbrella meta-analysis

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Importantly, none of these mechanistic observations confirm clinical effectiveness in humans

Mechanism and pharmacology Kruse et al

Acarbose plus metformin fixed-dose combination in the management of type 2 diabetes

It is underused because most patients do not know to ask for it