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Proton magnetic resonance spectroscopy (1H-MRS) has detected reduced GABA concentrations in the frontal and motor cortices, cerebellum, anterior cingulate cortex, and sensorimotor regions of ASD patients, along with decreased ratios of GABA/glutamate, N-acetylaspartate/creatine, GABA/creatine, and glutamate/creatine

Excessive doses, particularly those exceeding 3000mg daily without medical supervision, may disrupt the body's natural balance and potentially cause unwanted effects

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Fischer W, Currais A, Liang Z, Pinto A, Maher P (2019) Old age-associated phenotypic screening for Alzheimers disease drug candidates identifies sterubin as a potent neuroprotective compound from Yerba santa

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