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Contact your GP or diabetes care team within a few days if: Constipation persists despite lifestyle modifications and over-the-counter laxatives for more than one to two weeks

And some plans place GLP-1s in a higher tier of the pharmacy formulary with a higher out-of-pocket cost for the patient

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The faster you lose weight, the more muscle gets broken down for energy

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Maintenance: Once every 1-2 weeks