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Abstract Although physiological and hormonal differences between males and females can significantly alter drug absorption, distribution, metabolism, and excretion (ADME), most current pharmacotherapeutic guidelines remain sex neutral

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According to the results, it may help reduce fat deposition, increase energy expenditure, and improve overall metabolic performance by particularly targeting NNMT

This goes against the idea that greying accumulates due to the slow loss of melanin

Weydert & Cullen, 2010)