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CLINICAL RELEVANCE Evidence that glutathione is involved in the metabolic disturbances which underlie diabetes, obesity, insulin resistance, and the metabolic syndrome continues to grow as well

In addition to PARK6 (encoding PINK1) and PARK2 (encoding Parkin), other genes associated with Parkinsons disease, such as PARK7 (encoding the DJ-1 protein) and PARK8 (encoding the LRRK2 protein), are also thought to be mutated in patients with Parkinsons disease (Walter et al., 2019)

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The committee did not approve any peptide as a safe and effective drug or approve any clinical use