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GLP-1 medications (like Ozempic, Wegovy, Mounjaro) mimic the hormone to boost insulin, slow stomach emptying, and signal fullness, making them effective for type-2 diabetes and significant weight loss by reducing hunger and cravings

Sestrins repress mTORC1 signaling through an AMPK-TSC2-dependent (Budanov and Karin, 2014) manner

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