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Patients often report that their food cravingsparticularly for refined carbohydrates and sugardiminish naturally rather than through willpower alone, a phenomenon linked to improved glucose homeostasis and reduced dopamine dysregulation in reward centers

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3,4 GLP-1RAs mimic the action of endogenous GLP-1, activating GLP-1R, thereby enhancing insulin secretion, inhibiting glucagon release, delaying gastric emptying, and reducing food intake through central appetite suppression