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A small amount of the drug is metabolized via the cytochrome P-450 pathway (to be specific, CYP3A4 and CYP2E1) into NAPQI, which is extremely toxic to liver tissue, as well as being a strong biochemical oxidizer
For chronic conditions, such as ongoing inflammation or gut issues, it may take a bit longertypically two to four weeksto see significant changes
Behnaz Ashtari, Cellular and Molecular Research Center Iran University of Medical Sciences, Tehran, Iran