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Hypothyroidism contributes to OxS through an inefficient antioxidant defence system, opposite to hyperthyroidism, where increased ROS production promotes OxS and oxidative damage of thyroid cells ( Figure 1 ) (46)

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The greater stability of the amide group, compared with the ester group, is due to the lower positive-charge density on the electroposi-tive carbon

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It helps brighten skin and can fade mild pigmentation

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