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neurotoxicity
Current Genetics
Fusaric acid
Essential for the replication of pGreen transformations in Agrobacterium
Enables sensitive and specific amplification for diagnostic and research qPCR
Gefitinib N125 neurotoxicityGefitinib is an anti cancer agent similar to erlotinib. It functions through inhibiting the overexpressed or mutated epidermal growth factor receptor (EGFR) by binding its ATP binding site. Overexpression and mutation of EGFR are common in cancer cell lines and may lead to uncontrolled proliferation through the Ras signaling cascade. Gefitinib has been shown to induce tumor cell apoptosis in HaCaT cells, KG 1 cells, P39 cells, and CD34+ myeloblasts.
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