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Reported data show clinically meaningful HbA1c reductions and weight loss exceeding semaglutide monotherapy in the same population, supporting continued Phase 3 investigation

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Understanding semaglutide formulations and injection considerations Not all semaglutide products are identical in terms of injection technique requirements

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Reconstituted stability: 46 weeks refrigerated for both routes

Dose: 2mg twice daily (4mg total) Frequency: Morning and evening Duration: 4-6 weeks maximum Rest period: Equal to cycle length Splitting doses maintains more stable plasma levels throughout the day