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Briefly, 4 mg of MIA were dissolved in 40 L of sterile saline and this volume of solution was injected intraarticularly through the patellar ligament of the left knee joint of each rat that had been anesthetized using 50 mg/kg sodium pentobarbital by intraperitoneal injection

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Acta Diabetol 1995

This can lead to a more steady release of energy after meals instead of sudden spikes and crashes