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Consistent with attenuating the destructive effects of oxidative stress, presented evidence showed that Moringa oleifera extracts could effectively reduce the elevated levels of pro-inflammatory mediators such as tumor necrosis factor alpha (TNF-), IL-1, IL-6, cyclooxygenase-2 (COX-2), nitric oxide synthase (iNOS), and chemokine (MCP-1) to protect against exacerbated inflammation, under sustained conditions of hyperglycemia (Muhammad et al., 2016

Despite this, vacuolar transport of cargo occurs intermittently in plant cells, and receptors like VSRs must be efficiently recycled for subsequent rounds of cargo sorting