Lipid profiles, glycemic profiles, and liver function all improved following GLP-1 RA treatment
The enzymes catalyzing the reactions are as follows: glucose-6-phosphate isomerase (GPI), mannose-6-phosphate isomerase (PMI), phosphomannomutase (PMM), GDP-mannose pyrophosphorylase (GMP), GDP-mannose-3,5-epimerase (GME), GDP-L-galactose phosphorylase (GGP), L-galactose-1-phosphate phosphatase (GPP), L-galactose dehydrogenase (GalDH), L-galactono-1,4-lactone dehydrogenase (GalLDH), ascorbate peroxidase (APX), monodehydroascorbate reductase (MDHAR), dehydroascorbate reductase (DHAR), ascorbate oxidase (AO), and glutathione reductase (GR)
Gastrointestinal studies for motility issues
Survodutide is being studied for weight loss, cardiovascular risk reduction , and a type of fatty liver disease called metabolic dysfunction-associated steatohepatitis (MASH)
Appetite suppression can make it harder to meet calorie and carbohydrate needs, affecting fueling, endurance and recovery
10.3389/fpubh.2025.1690211 Front Public Health
