There is no downtime either way
According to Jette et al., CJC-1295 may achieve that as it appears to be based on the core motif of the endogenous GHRH
In vitro study corroborated that the suppression of the ROS/TXNIP/HIF-1 pathway, which was presumably associated with the mitochondrial dysfunction in ferroptosis, fosters the ratio of retina-specific Treg cells, notably attenuating ocular inflammation and optic disc edema (54)
Sermorelin operates as a synthetic growth hormone-releasing hormone (GHRH) analogue, mimicking the natural hormone produced by the hypothalamus
Improved Muscle Growth and Recovery Boosts protein synthesis and muscle repair
That is why tesamorelin carries FDA approval as EGRIFTA, EGRIFTA SV, and EGRIFTA WR for that specific use