Fan, Z., Huang, J., Huang, H
It doesnt suppress endogenous testosterone, doesnt aromatize into estrogen, and carries no direct androgenic side effects
Observations in cultured aortic smooth muscle cells suggested that GHRP-2 may counter the production of peroxides triggered by OxLDL, prevent the suppression of the IGF-I receptor, and potentially block apoptosis
However, CJC-1295 (especially the DAC version) can cause sustained elevation in IGF-1, whichif mismanagedmay increase the risk of: Insulin resistance Carpal tunnel syndrome Soft tissue growth (in rare, prolonged cases) Pituitary overstimulation That said, these issues are more often associated with excessive dosing or continuous high-frequency use
PMID: 40813933 SSRN2025 Jan 14
Development of plasma ghrelin level as a novel marker for gastric mucosal atrophy after Helicobacter pylori eradication