There is already an appreciation within the medical literature that a narrow focus within outcomes trials misses the wider benefits of GLP-1 RAs across the CKM spectrum, and there are calls to review the design and analysis of outcomes trials in the CKM space to include more endpoints [44]
Extended clinical trials and real-world data are crucial to understand their lasting impact on weight, metabolic health, and potential side effects
Quality of life and glucose control after 1 year of nationwide reimbursement of intermittently scanned continuous glucose monitoring in adults living with type 1 diabetes (FUTURE): a prospective observational real-world cohort study
Vitamin B1 helps provide energy to cells via carbohydrate metabolism
GLP-1 receptor agonists like semaglutide mimic the action of naturally occurring GLP-1 hormones
Daniels's team investigated how GLP-1 drugs regulate thirst and drinking behavior using Brattleboro rats, a common animal model of a rare disorder called diabetes insipidus, which causes the animal to excessively urinate and subsequently drink water