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Genetic polymorphisms in DIOs and other SelPs significantly influence individual susceptibility to thyroid dysfunction and response to Se supplementation

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Research has identified several contributing mechanisms: dysregulated innate immune signalling, oxidative stress from reactive oxygen species damaging skin cells, and impaired barrier function that leaves the skin more reactive to triggers it would otherwise tolerate

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The 2022 clinical study that showed 22% hair count improvement included participants with androgenetic alopecia of both sexes