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Some specific examples of this phenomenon include GPx-1 preventing hepatocyte apoptosis caused by ROS but potentiating hepatocyte apoptosis caused by RNS

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J Pediatr Endocrinol Metab 16(1):63-70

Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions

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Several binding studies suggest KPV does not directly bind MC-1R and does not increase cAMP levels