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NASH model mice treated with L-carnitine exhibited significant improvements in hyperglycemia and hyperinsulinemia (29, 59)

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BH3 domain of BNIP-3 interacted with anti-apoptotic protein to form dimers, which was able to promote the apoptosis (Luo et al., 2021

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Clinical enthusiasm should remain tempered until larger, independently conducted trials establish both safety and efficacy

Of note, most of these studies were conducted exclusively in younger adult male rodents