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Use of weight loss medications in patients after bariatric surgery

GIP receptor activation enhances insulin secretion in a glucose-dependent manner and, based on preclinical and early clinical data, may improve insulin sensitivity in adipose tissue

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But in contrast to GLP-1GIP, GLP-1GIPLani exhibitied similar effectiveness to Lani in promoting the expression of the PPAR target gene PDK4 in GLP-1R and GIPR-expressing HEK293T cells transfected to co-express PPAR, PPAR or PPAR (Fig

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Here's what we know and what's still TBD