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On an immunomodulatory level, anti-inflammatory factors secreted by the amniotic membrane (e.g., SLPI/elafin) synergize with MenSC-derived paracrine cytokines such as IDO, PGE 2 , and TGF-, promoting the polarization of macrophages from the pro-inflammatory M1 phenotype to the regenerative M2 phenotype
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Some people say they feel a sense of relaxation and improved well-being after receiving the treatment, while others may not notice any immediate effects
Journal of Neuroengineering and Rehabilitation 10: 46