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Pancreatitis and gallbladder issues: Severe abdominal pain that radiates to the back, nausea, fever, or vomiting while using GLP-1s may indicate inflammation of the pancreas, while upper right abdominal pain, jaundice, fever, and nausea can be due to gallbladder issues such as gallstones

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The samples were centrifuged at 13000 g for 10 min at 4 C and the supernatant was collected and detected by HPLC to analyze the biostability of M-CuP and D-CuP against proteinase K