Many gastrointestinal effects are transient, but persistent or severe symptoms should not be ignored
10.7 Clinical Bottom Line GLP-1 receptor agonists: Do not inherently cause universal nutrient depletion May increase intake-related vulnerability Require structured dietary strategy Benefit from risk-based monitoring Should be accompanied by protein prioritisation Weight loss and nutritional adequacy are not mutually exclusive
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Trimetazidine attenuates exhaustive exercise-induced myocardial injury in rats via regulation of the Nrf2/NF-B signaling pathway
These include but are likely not limited to chronic hyperglycemia, hypertension, dyslipidemia, obesity, insulin resistance, sodium retention, neurohormonal activation and low-grade inflammation, all related to the metabolic syndrome [9, 10]