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Romanov, R

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PubMed 7.Becejac T et al

Studies confirm 50% drops by midlife, linking to aging symptoms.[1][9] Restoring NAD+ has been shown in animal studies to improve lifespan and healthspan, with human trials indicating benefits in muscle function and cognitive performance

Results Cisp administration (8 mg/kg, IP) significantly impaired liver function, increased oxidative stress, promoted apoptosis (increased BAX, CASPASE-3, and decreased BCL2) and disrupted homeostasis by increasing the ferroptosis upstream ferritinophagy (decreased ferritin and increased NCOA4)

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