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In comparison, only 1.5% to 2% of people taking a placebo reported constipation

The queries for the articles about the gut-liver axis: ((GLP-1RAs[Title/Abstract]) OR (GLP-1R agonists[Title/Abstract]) OR (GLP-1 receptor agonists[Title/Abstract]) OR (GLP-1 receptor[Title/Abstract])) AND ((liver[Title/Abstract]) OR (hepatic[Title/Abstract]) OR (HCC[Title/Abstract])) AND (microbiota[Title/Abstract])

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Dulaglutide (Trulicity) Dulaglutide (Trulicity) has a similar mechanism of action to semaglutide

Gastrointestinal side effects, including heartburn, are most likely when increasing your dose and often improve with time