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Food and Drug Administration (FDA) and Developed by 22nd Century Group, Inc., The tobacco was developed over 10 years of research and through more than 50 government-funded, independent clinical trials by or for esteemed public health institutions and universities, including: the FDA

What the Science Says About Safe Smoking Levels Studies on Low-Level Smoking Multiple studies have busted the myth of safe smoking. A major review published in the BMJ found that smoking just one cigarette per day increases the risk of heart disease by 48% compared to non-smokers

Penn State developed an electronic cigarette dependence index that helps to assess nicotine dependence levels

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