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Obviously, in markets where plain packaging is mandatory for tobacco products, a shrink film embedded with brand logos (or attractive design elements) would be a definite no-go
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In the pioneering studies by Sleiman et al., the major TSNA formed from the reaction of nicotine with nitrous acid, under conditions that modeled indoor environments, was 4-methylnitrosamino-4-(3-pyridyl)-butanal (NNA), as discussed above 5 (Scheme 1)
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