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These pathways can have a downstream effect on autonomic nervous system regulation, potentially raising heart rate

Semaglutide is a GLP-1 receptor agonist while tirzepatide activates both GIP and GLP-1 receptors, which can lead to larger average weight loss in some trials

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What to do if you experience an increased heart rate after taking semaglutide If you take semaglutide and your heart starts to beat rapidly, please contact your healthcare provider as soon as possible