But their use has become controversial due to a lack of evidence on their efficacy as anti-smoking aids, warnings about possible long-term health effects and numerous studies showing that teen use is a direct gateway to traditional cigarette smoking
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(1) In 2018, cigarette smoking imposed a financial burden of over $600 billion on the United States
Additionally, comparing the flavor components indicated that the content of the carotenoid degradation products, Maillard reaction products, chlorophyll degradation products, and cembranoid degradation products was lower in the moldy cigar tobacco leaves than in the healthy leaves, with a total decline of 12.75%
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