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the total levels, from each smoking article, of nictotine, nicotine-free dry particulate matter (NFDPM), carbon monoxide (CO), water, and the total particulate matter (TPM) is also shown

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2023, Vatrella et al

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In addition, observational studies are susceptible to bias and confounding and any reported associations may not reflect causal relationships between the phenotypes (Mann 2003)