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Evidence suggests that nicotine use during adolescence and young adulthood has long-term impacts on brain development, and tobacco use remains the leading cause of preventable death in the U.S., said Ohio Department of Health Director Amy Acton, MD, MPH

That flavor variety and nicotine strength are central to why the product has become popular, and also central to why regulators have raised concerns

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Yet, there were still some things that left us wanting more, particularly in the build-quality category

DOI: 10.1097/00000542-200512000-00025 6