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The most apical of these complexes are the Tight Junctions (TJs), formed of multiple protein strands that maintain close opposition of adjacent cell membranes ( Figure 1 Adherens junctions form another junctional layer, which consists of the transmembrane protein E-cadherin bound to cadherin-catenin complexes in the cytoplasm of adjacent cells ( Despite forming a tight barrier, basement membrane pores are important for enabling cells to move between the epithelium and lamina propria and in reverse

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Medical research has mapped those consequences with striking precision, from the first minutes after a cigarette to the decade-long arc of recovery when you quit