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Elmorsy et al

10 mg in 1 mL floor of total dose 20 units ( 0.2 mL ) on a 0.3 mL syringe for a 2000 mcg dose

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When a low dose of aspirin is administered orally (most commonly 81 mg), its context-sensitive drug disposition via the portal circulation combined with the difference in IC50 values for COX-1 vs COX-2 both contribute significantly to the high selectivity by which low dose oral aspirin inhibits platelet COX-1 vs other COX-2 found in other nucleated tissues such as the vascular endothelium (Pedersen & FitzGerald, 1984

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