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5 In the literature, commonly reported oral symptoms related to e-cigarette use include xerostomia, burning sensation, irritation, pain, oral ulceration, nicotine stomatitis, hairy tongue and angular cheilitis

We focused on individuals with low SES and with SPD because they are, respectively, the largest subpopulation with significantly elevated smoking prevalence and a subpopulation with very high smoking prevalence [9,10,11, 16,17,18, 42]

In addition, PGE2 and IL17, important mediators of inflammation, are elevated in both CNV mouse models and AMD patients 54,55 and are further increased by smoking 56

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