By stimulating the production and release of growth hormone, UK clinical trials have found that Ipamorelin promotes various physiological processes, including muscle growth, fat metabolism, and tissue repair
The branded Sermorelin product (Geref) was FDA-approved in 1997 for diagnosis and treatment of pediatric growth hormone deficiency
However, GHRP-6's pronounced appetite stimulation and broader hormonal footprint, including cortisol and prolactin elevation at higher doses, make it a less refined option than newer secretagogues like ipamorelin
Animal studies show that increased growth hormone levels from ipamorelin treatment can produce decreases of approximately 14% in fat mass without dietary modifications
Reconstitute each peptide in its own vial and never combine them into the same syringe
Sermorelin & Ipamorelin and Role of Ghrelin Receptors Ipamorelin is thought to be highly selective for GHS-R1a, the primary receptor for ghrelin