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Given the rising global prevalence of e-cigarette and heated tobacco product use, particularly among younger populations, there is an urgent need for longitudinal studies assessing their hepatotoxic potential, including device- and flavor-specific effects

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The relative abundance of Rhodotorula was highest in T0 (30.09%), followed by T3 (25.02%), T1 (15.00%), and T2 (9.34%), whereas Aspergillus exhibited its highest abundance in T1 (20.93%), followed by T2 (19.89%), T3 (11.80%), and T0 (9.82%)

The latest proposal is open to public comment for 60 days through October 15, the FDA said.

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