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Cigarette smoke upregulates SPRR3 by favoring c-Jun/Fra1 heterodimerization in human bronchial epithelial cells

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The Department of Health and Social Care (DHSC) has announced that it is opening a consultation on Monday to seek views on the introduction and design of pack inserts for tobacco products, such as cigarettes and rolling tobacco

The researchers found that despite not being cancerous, more than nine out of every 10 lung cells in current smokers had up to 10,000 extra genetic changes mutations compared with non-smokers, and these mutations were caused directly by the chemicals in tobacco smoke

However, it is worth mentioning that some individuals may perceive certain psychological or social benefits from smoking, though these are subjective and not related to any inherent advantages of smoking itself