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doi: 10.1038/nmeth.3213

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All groups experienced reductions in brachial and aortic blood pressure and increases in plasma NO metabolites, but only the WBVT groups showed significant decreases in augmentation index (AIx), with the CIT + WBVT group demonstrating the greatest improvement

However, further examination revealed that the GSH binding site is very similar to that in bacterial Ochrobactrum anthropi GST (OaGST) as an H-site binding 21

Nausea, vomiting, diarrhea, and constipation were the most common gastrointestinal adverse effects

CMS originally planned to fold this into permanent Part D coverage through the BALANCE model in 2027, but that was delayed in April