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But by the end of the Lewis-Morris chapter, it became obvious that Matthews was only trying to top himself, to go beyond what he'd already written

These cigarettes were designed with tiny ventilation holes in the filters, which dilute the smoke with air and make it seem less harsh

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Besides, more in-depth studies are needed to explore the effects of smoking on other enzymes, such as CYP3A4, and on renal transporters, as well as the possibility of monitoring and tailoring drug dosages by phenotypic and genotypic tests (e.g