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A drugs half-life is essentially the time frame of how long it takes for the concentration of the drug to become reduced to 50% or

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A double-floxed inverse open reading frame (DIO) allowed to restrain the expression of CatCh (Ca 2+ -translocating channelrhodopsin) or Jaws (red-shifted cruxhalorhodopsin) to VTA dopaminergic neurons of DAT iCRE mice