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They also highlight that histone lactylation in CD8 T cells can enhance effector functions and restrain tumor growth, underscoring the substrate- and cell typespecific nature of lactylation [177]

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Also, since lithium increases both CaMKK2 activity and protein abundance, it is possible that CaMKK2 may be involved in mediating the acute as well as longer-term effects of lithium such as preventing episode recurrence [176]

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