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Abnormal activation of TLRs leads to an exaggerated autoimmune response with increased production of cytokines such as IL17A and IL22, which are responsible for hyperproliferation and abnormal differentiation of keratinocytes, ultimately leading to the formation of psoriatic plaques (Sun et al., 2019)

If I rush, I no longer have the time afforded to me to sit down and have a cig

This makes them an interesting alternative to the classic cigarette for many smokers

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