PMID: 32690941
Luo, Z., Zhao, Q., Liu, J., Liao, J., Peng, R., Xi, Y., & Diwu, Z
Kentuckys Board of Pharmacy follows the federal rule, with the caveat that compounding generally should not occur when a commercially available product exists except in specific patient-specific circumstances
The best choice depends on current weight and BMI, weight-related medical conditions, blood sugar status, cardiovascular risk, liver health, kidney function, medication history, side-effect risk, muscle mass and nutrition status, cost and access, patient preference, and long-term maintenance planning
In the SURPASS-2 trial (published in The New England Journal of Medicine in 2021), tirzepatide at 5, 10, and 15 mg was compared with semaglutide 1 mg in 1,879 adults with type 2 diabetes on metformin over 40 weeks
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