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I don't know what exactly they used, but I have worked with raw tobacco from all over the world, and there just simply is no such thing as raw, unflavored, un-augmented tobacco that smells something like Orlik Golden Sliced or Dunhill Light Flake." Another example is McClellend, whose Virginias I've always appreciated and accepted as unflavored, but let's face it, that distinctive tin scent that we all associate with McClellend is not a natural evolution of the aging process

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In addition, smokeless tobacco altered the oral microbiome in OSCC patients, significantly enriching genera such as Staphylococcus , Fusobacterium , and Campylobacter , known for producing tobacco-specific nitrosamines

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