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PLoS One (2010) 5(8):e11934.10.1371/journal.pone.0011934 74 Metzler-GuillemainCVictoreroGLepoivreCBergonAYammineMPerrinJet alSperm mRNAs and microRNAs as candidate markers for the impact of toxicants on human spermatogenesis: an application to tobacco smoking