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They found that two-thirds of changes in gene activity could be explained by vape flavor and device type, suggesting the chemical makeup of vaping products and the design and configuration of devices play a major role in their biological effects

"RECORDINGS VIEW

A number of advocacy groups, lawsuits filed against Juul, and even state and federal governments are currently challenging e-cigarette manufacturers ability to offer flavors other than traditional cigarette flavors

The units we tested have hoses ranging from as short as just over 15 inches to as long as 30 feet

The Bottom Line: Nicotine leads to addiction, and addiction leads to a brain disease. Putting aside the controversy of whether vaping is a win or loss for public health, I think we can all agree that nicotine (the psychoactive addictive chemical found in e-cigarettes and tobacco smoke) inevitably leads to addiction, and that addiction is a brain disease

JAMA Network Open