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Some patients may need dose adjustment at a faster pace than others, and other patients may need to slow down how quickly they increase the dose of the medication

Upon germline removal, DAF-16/FOXO enters the intestinal nuclei and regulates downstream target genes 6

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Amaral AU, Wajner M (2022) Pathophysiology of maple syrup urine disease: focus on the neurotoxic role of the accumulated branched-chain amino acids and branched-chain -keto acids

HRT patches and nicotine patches [which have been around for a while] require robust clinical trials to prove they have an effect

doi: 10.1177/10742484221146371