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This counterintuitive observation led scientists to investigate whether components of cigarette smoke could be responsible for this unexpected protective effect

10.1016/j.jadohealth.2009.02.004 3

You will have to take my word for it

However, recent investigations of the puffing topography (42, 43) might suggest further refinements for a better adoption of machine smoking to HTP

Majority of the vendors sell loose cigarettes, allowing users to bypass pictorial warnings entirely and making tobacco accessible for as little as 15-18

COPD is typically caused by long-term exposure to irritants in the lungs, and the biggest culprit is smoking