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Nicotine may not be a good fit if it causes palpitations, anxiety, irritability, insomnia, headaches, nausea, dizziness, blood pressure changes, cravings, emotional crashes, increased histamine symptoms, or a need to keep using it to feel normal

The surveys collected information about patients smoking status, treatments, and events such as a recurrence or spread of cancer

As for whether oral nicotine pouches directly increase cancer risk, the answer remains unclear

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